Wednesday, October 24, 2018
Catalyst Biosciences, Inc., a clinical-stage biopharmaceutical company focused on developing novel medicines to address hematology indications, announced that it has received a Notice of Allowance from the Japan Patent Office (Patent No. 6363600 (2015-524250)) for claims in the Company’s international patent PCT/US2013/032616, covering modified Factor X polypeptides and the uses thereof. The patent includes claims that cover modified coagulation Factor X polypeptides, including Factor Xa and other forms of Factor X, and use of modified Factor X polypeptides for certain bleeding disorders.
“Modified Factor X polypeptides may represent an attractive opportunity for broad coagulation control,” said Nassim Usman, Ph.D., chief executive officer of Catalyst. “We continue to strengthen our leadership position in intellectual property for modified coagulation factors to treat bleeding disorders. The expansion of our Factor X intellectual property rights into Japan builds on our existing Factor X patent in the U.S. and our global Factor VIIa and Factor IX patent portfolios.”
Factor X is a clotting factor that has the potential to be used as a “universal procoagulant.” Once activated to Factor Xa, it activates the final common pathway of coagulation proteins, leading to the formation of a blood clot. Because of its downstream clotting pathway activity, a safe and effective Factor Xa product could potentially treat hemophilia, blood loss in trauma and surgery in individuals with normal coagulation systems, and those who are bleeding as a result of taking anti-platelet agents or anticoagulants. In preclinical studies, Catalyst has identified Factor Xa variants that have demonstrated superiority to competing Factor Xa candidates in clinical development.
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Key Facts
News Category: Intellectual Property
Company
Catalyst Biosciences Inc
Japan Patent Office
Country Asia-Pacific > Japan
North America > United States of America